Three recent cases of polio have been registered in Kandahar province, one in Kandahar City and two others in Dand and Panjwai districts, public health officials reported on Wednesday.
Polio cases have not been registered in Kandahar in the past 20 months.
Officials claim that the disease has spread from Pakistan, as most cases of the disease in Afghanistan are said to occur on the Afghan-Pakistani border in the country's eastern provinces.
Reports indicate that immigrants from northern Waziristan of Pakistan have brought polio to Khost province, making it likely for the disease to spread to other parts of the country.
Khost director of the Public Health Department has confirmed the reports, adding that many children coming from northern Waziristan have not been vaccinated.
Afghanistan, Pakistan, and Nigeria are the only three countries in the world where polio has yet to be fully eradicated. There have been nine confirmed cases of Polio in Afghanistan this year.
There were 14 cases in 2013, 37 in 2012 and eight in 2011.